Ημερομηνία / Ώρα
Ημερομηνία - 15/11/2018 - 18/11/2018
Highlights from the FRM program
The “Breaking News” Lecture
Located on the X-chromosome, the fragile X mental retardation 1 (FMR1) gene is one among only very few so-called expansions genes, characterized by triple nucleotide repeats (in this case CGGn). Widely recognized for its neuropsychiatric pathologies, it in recent years has been increasingly also recognized as very important for follicle recruitment and development in the ovary. How this gene function, whether in brain or ovary, has, however, for the longest time not been understood.
A recent study in August published in SCIENCE (Greenblatt & Spradling, Science 2018; 361;709-712) now for the first-time sheds important light on this subject. Ethan J. Greenblatt, PhD, one of the two authors of the study, will present a talk built on this work under the title: “Understanding translational dysfunction in fragile X-associated neural and reproductive disorders” as this year’s Breaking News Lecture, which will open the conference.
Leading themes of the conference
Purely accidentally, the FMR1 gene has become one of two leading themes in this year’s conference. Talks involving this gene are spread throughout the program, offering testimonial to this gene by some being called the most important “unknown” gene in reproductive medicine.
The other subject that evolved as a leading theme for this year’s conference is more clinical and involves the chromosomal testing of preimplantation-stage embryos, called preimplantation genetic screening (PGS) or, more recently, preimplantation genetic testing for aneuploidy (PGT-A). The last year has brought radical changes to the understanding of embryo mosaicism and, therefore, to the clinical utilization of PGS/PGT-A in association with IVF. Again spread throughout the program, various speakers will be addressing the subject.
Other important subjects addressed by the conference among many others are the polycystic ovary syndrome (PCOS), and especially how, when it comes to infertility, the various phenotypes of PCOS have for the longest time been misunderstood, and the many ethical issues, which in reproductive biology and reproductive clinical practice always bubble right under the surface.
Sessions 9 (Hot topics) and 10 (Most interesting recent presentations and still unpublished data), the two concluding sessions on Sunday morning, will be among the most interesting, not only featuring some of the best-known speakers but also offering a look into the future, outlining where reproductive biology and medicine, likely, will go over the next few years.
Like every year, pre-congress workshops are split between clinical and basic science topics.
Norbert Gleicher, MD chairs a workshop that suggests a necessary paradigm shift in IVF practice since currently too many women are pushed into egg donation too early. Raoul Orvieto, MD, in turn, chairs a workshop that suggests a paradigm shift in how recent “add ons” to IVF have hurt IVF outcomes more than they helped. David Albertini, PhD chairs a workshop that will attempt to make sense of what is fact and fiction when it comes to cryopreservation of gametes and, finally, Gist Croft, PhD, will demonstrate human embryos as never seen before, based on some of the unique studies at the Brivanlou Laboratory at Rockefeller University.
Register today to enjoy the reduced rates!
Until October 1, 2018
Reserve your room
New York Marriott
259.00 USD per night
Exciting 4 pre-conference workshops will be held on
Thursday, November 15, 2018,
2:00 – 6:00 P.M.
Clinical Fertility Day
Leading fertility experts will address some of the most complex fertility issues in direct Q&A sessions on Sunday, November 18, 2018, 2:00 – 6:00 P.M.
The 3rd FRM Conference
frm2018.cme-congresses.com | [email protected]
The Foundation for Reproductive Medicine
21 E 69th Street
New York, N.Y. 10021
Tel: (646) 882-0840
Fax: (212) 994-4499